Sébastien Tremblay 2

Affiliation: Assistant Professor, Dept. of Psychiatry & Neuroscience, CERVO Brain Research Center, Université Laval

Talk Title: Reading and writing wirelessly in the primate brain

Abstract: Cognitive research in non-human primates has typically involved heavy movement restraints to accommodate bulky brain recording and stimulation equipment. Consequently, it is not clear whether the insights generated in constrained laboratory settings generalize to more ecologically-valid contexts where primates are free to move and interact with their environment naturally. I will present new data collected in semi-restrained and fully unrestrained monkeys during the performance of cognitive tasks as well as natural social interactions. I will also present new optogenetics techniques for the primate brain including viral delivery methods as well as chronic illumination technologies allowing wireless control of specific cell populations in freely-moving primates. I will discuss applications of such technologies for both basic research and clinical applications for primates, including humans.

Relevant papers

- Testard, C.*, Tremblay, S.*, Parodi, F., DiTullio, R, Acevedo-Ithier, A., Gardiner, K., Körding, K., Platt, ML. (2024) Neural signatures of natural behavior in socializing macaques. Nature (in press)

- Tremblay, S.*, Testard, C.*, DiTullio, R., Inchauspé, J., Petrides, M. (2023) Neural cognitive signals during spontaneous movements in the macaque. Nature Neuroscience

- Tremblay, S., International Consortium of NHP users, Shenoy, K., DiCarlo, J., Platt, M.  (2020) An Open Resource for Non-human Primate Optogenetics. Neuron

Seminars are now offered as hybrid in-person meetings.

Physical Location: Abramsky Hall Room 002

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Abramsky Hall, Rm 002 Kingston ON K7L 3N6